Peer-reviewed publications contributing to advances in medical genetics and personalized medicine
Selected Publication
Falana SL, …, Rohani L, …, Churko JM. “Modelling arrhythmogenic cardiomyopathy fatty fibro pathology with PKP2-deficient epicardial cells derived from human iPSCs”.
Commun. Biol. Oct 27;8(1):1502.
Juraskia AC, …, Rohani L**, Willerth SM**. “3D bioprinting for organ and organoid models and disease modeling”.
Expert Opinion on Drug Discovery. Jul-Dec ; 18(9) : 1043-1059.
Bourhill T, Rohani L, …, Johnston RN. “Modulation of Reoviral Cytolysis (II): Cellular Stemness”.
Viruses. 15(7), 1473.
Safabakhsh S, … , Collins C**, Rohani L**, Laksman Z**. “Isolating nuclei from frozen human heart tissue for single-nucleus RNA sequencing”.
Current Protocols. Jul;2(7):e480.
Nath SC, …, Rohani L, …, Rancourt DE. “Fluid shear stress promotes embryonic stem cell pluripotency via interplay between β-catenin and vinculin in bioreactor culture”.
Stem Cells. Sep;39(9): 1166 1177.
Borys BS, …, Rohani L, …, Kallos MS. “Overcoming bioprocess bottlenecks in the large-scale expansion of high quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors”.
Stem Cell Research & Therapy. Jan 13;12(1):55.
Rohani L, …, Rancourt DE. “Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells”.
(Outreached by news and media coverage: e.g., The Niche Knoepfler Blog, Science in Vancouver, Biobanking.com (B2B News), Gladstone Institutes News, THE STEM CELL PODCAST, etc.).
Nat. Communications Biology (Nature Portfolio). Sep 7;3(1):492.
Rohani L*, Machiraju P*, …, Greenway SC. “Reversible impaired mitochondria in dilated cardiomyopathy with ataxia syndrome-iPSC-derived cardiomyocytes by mitochondrion-targeted peptide SS-31”.
Can J Cardiol. Apr;36(4):554-563.
Wallenborn M, … , Rohani L, …, Holland H. “Molecular analyses of glioblastoma stem-like cells and glioblastoma tissue”.
PLOS One. Jul 7;15(7):e0234986.
Borys BS, … , Rohani L, …, Kallos MS. “Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors”.
Journal of Biotechnology. Oct 10; 304:16-27.
Rohani L*, Johnson AA*, …, Holland H. Concise Review: “Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells”.
STEM CELLS Translational Medicine. Dec;7(12):867-875.
Wallenborn M, …, Rohani L, … , Holland H. “Comprehensive high-resolution genomic profiling and cytogenetics of human chondrocyte cultures by GTG-banding, locus-specific FISH, SKY, and SNP-array”.
Eur Cell Mater. Apr 23; 35:225-241.
Rohani L, …, Stolzing A. “Generation of human induced pluripotent stem cells using non-synthetic mRNA”.
(Syntheticbiology for cell fate engineering and cellular reprogramming with non-synthetic mRNA.).
Stem Cell Research. May;16(3):662-72.
Rohani L, …, Stolzing A. “The aging signature: a hallmark of iPS cells?”.
Aging Cell. Feb;13(1):2-7.
Maharlooei MK, …. , Rohani L, … , Omrani GR. “Adipose tissue derived mesenchymal stem cell (ADMSC) promotes skin wound healing in diabetic rats”.
Diabetes Research and Clinical Practice. Aug;93(2):228-34.
Rohani L, …. , …, Baharvand H. “Embryonic stem cell sphere: A controlled method for production of mouse embryonic stem cell aggregates for differentiation”.
International Journal of Artificial Organs. Mar;31(3):258-65.
Rohani L**, Toms D*, …, Ungrin M**, Rancourt DE**. “High-throughput combinatorial screening tunes cell fate dynamics in mass-produced liver organoids”.
(Synthetic Smart Organoids pitch — Nominated and accepted to The BluePrint (The Engine, MIT Tough Tech); provisional patent in preparation with Innovate Calgary (University of Calgary TTO).
(manuscript in preparation).
Khalilitousi MS, …, Rohani L**. “Current Progress and Future Outlook for Synthetic Gene Circuits in Cardiovascular Therapy”.
Biomolecules. (under revision) (Featured in Bioinformatics and Systems Biology Section).
Almutawaa W, Rohani L, Rancourt DE. “Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors”.
Methods Mol Biol. Springer Nature. Bioreactors in Stem Cell Biology. 1502:53-61.
(Humana Press, New York, NY).
Schedule a consultation to discuss your genetic health concerns and explore personalized solutions.
