Publications

Peer-reviewed publications contributing to advances in medical genetics and personalized medicine

Publications
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Selected Publication

2025

Doi

Huang K*, Ashraf M*, Rohani L*, …, Laksman ZW. “Atrial fibrillation related titin truncation is associated with chamber-specific phenotypes and atrial myopathy in patient-derived human iPSC disease models”.

Circulation: Genomic and Precision Medicine. Jan 24:e004412.

2023

Doi

Juraskia AC, …, Rohani L**, Willerth SM**. “3D bioprinting for organ and organoid models and disease modeling”.

Expert Opinion on Drug Discovery. Jul-Dec ; 18(9) : 1043-1059.

2023

Doi

Bourhill T, Rohani L, …, Johnston RN. “Modulation of Reoviral Cytolysis (II): Cellular Stemness”.

Viruses. 15(7), 1473.

2022

Doi

Safabakhsh S, … , Collins C**, Rohani L**, Laksman Z**. “Isolating nuclei from frozen human heart tissue for single-nucleus RNA sequencing”.

Jul;2(7):e480.

2021

Doi

Nath SC, …, Rohani L, …, Rancourt DE. “Fluid shear stress promotes embryonic stem cell pluripotency via interplay between β-catenin and vinculin in bioreactor culture”.

Stem Cells. Sep;39(9): 1166 1177.

2021

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Borys BS, …, Rohani L, …, Kallos MS. “Overcoming bioprocess bottlenecks in the large-scale expansion of high quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors”.

Stem Cell Research& Therapy. Jan 13;12(1):55.

2020

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Rohani L, …, Rancourt DE. “Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells”.

Nat. Communications Biology (Nature Portfolio).(Outreached by news and media coverage: e.g., The Niche Knoepfler Blog, Science in Vancouver, Biobanking.com (B2B News), Gladstone Institutes News, THE STEM CELL PODCAST, etc.).

Sep 7;3(1):492.

2020

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Rohani L*, Machiraju P*, …, Greenway SC. “Reversible impaired mitochondria in dilated cardiomyopathy with ataxia syndrome-iPSC-derived cardiomyocytes by mitochondrion-targeted peptide SS-31”.

Can J Cardiol. Apr;36(4):554-563.

2020

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Wallenborn M, … , Rohani L, …, Holland H. “Molecular analyses of glioblastoma stem-like cells and glioblastoma tissue”.

PLOS One. Jul 7;15(7):e0234986.

2019

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Borys BS, … , Rohani L, …, Kallos MS. “Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors”.

Journal of Biotechnology. Oct 10; 304:16-27.

2018

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Rohani L*, Johnson AA*, …, Holland H. Concise Review: “Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells”.

STEM CELLS Translational Medicine. Dec;7(12):867-875.

2018

Doi

Wallenborn M, …, Rohani L, … , Holland H. “Comprehensive high-resolution genomic profiling and cytogenetics of human chondrocyte cultures by GTG-banding, locus-specific FISH, SKY, and SNP-array”.
Eur Cell Mater. Apr 23; 35:225-241.

2016

Doi

Rohani L, …, Stolzing A. “Generation of human induced pluripotent stem cells using non-synthetic mRNA”.

Stem Cell Research. May;16(3):662-72.

(Syntheticbiology for cell fate engineering and cellular reprogramming with non-synthetic mRNA.).

2014

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Rohani L, …, Stolzing A. “The aging signature: a hallmark of iPS cells?”.

Aging Cell. Feb;13(1):2-7.

2011

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Maharlooei MK, …. , Rohani L, … , Omrani GR. “Adipose tissue derived mesenchymal stem cell (ADMSC) promotes skin wound healing in diabetic rats”.

Diabetes Research and Clinical Practice.

Aug;93(2):228-34.

2008

Doi

Rohani L, …. , …, Baharvand H. “Embryonic stem cell sphere: A controlled method for production of mouse embryonic stem cell aggregates for differentiation”. International Journal of Artificial Organs.
Mar;31(3):258-65.

Under peer-review

2025

Rohani L**, Toms D*, …, Wiess R**, Ungrin M**, Rancourt DE**. “High-throughput combinatorial
screening tunes cell fate dynamics in mass-produced liver organoids”.(manuscript in preparation).

2025

Sharma S, …, Moon T**, Rohani L**, Weiss R**. “Synthetic gene regulatory networks and biological
circuit designs: Engineering smarter medicines for cardiovascular diseases”. (manuscript in preparation).

Book chapter

2016

Doi

Almutawaa W, Rohani L, Rancourt DE. “Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors”.

Methods Mol Biol. Springer Nature. Bioreactors in Stem Cell Biology. 1502:53-61.

(Humana Press, New York, NY).

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